Canesten Combi is a dual action treatment for vaginal thrush. The pessary is inserted into the vagina to fight infection at the source whilst the cream helps soothe itching and discomfort. Canesten products contain clotrimazole an effective antifungal which helps treat fungal conditions such as yeast infections and thrush. Clotrimazole helps to prevent fungal bacteria from growing on the affected area. Unlike antibiotics clotrimazole products are usually applied directly to the skin to inhibit fungal growth directly.